The Stadium Orthopaedic & Sports Medicine Centre The Stadium Orthopaedic & Sports Medicine Centre: (02) 8323 6500
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Synvisc-One Injection

What is Osteoarthritis?

Osteoarthritis is the progressive degeneration of the cartilage covering the ends of the bones in joints. A healthy joint is lubricated by synovial fluid, which reduces friction between the surfaces. Gradual ‘wear and tear’ on your joints can cause this cartilage to break down, and the synovial fluid becomes ineffective at lubricating the knee. This can cause areas of cartilage covering the bones to totally wear away, exposing the underlying bone and causing them to rub against each other. Symptoms of osteoarthritis include joint pain, tenderness, stiffness, locking or swelling in the affected joints.

What is Synvisc One?

Synvisc One is a gel-like product (hylan G-F 20) containing properties similar to the natural hyaluronic acid found in healthy synovial fluid.

How does it work?

6mL of Synvisc One is injected into the knee joint. This substance acts as a lubricant for the knee, replacing the diseased synovial fluid, which was ineffective in protecting the knee. This helps to increase the knee’s ability to absorb shocks and reduce pain, while also improving mobility.

Benefits of Synvisc One?

  • A single 6mL injection of Synvisc One can provide pain relief in the knee for up to 6 months
  • Short term studies have found Synviscviscosupplementation to significantly improve pain on weight-bearing, pain at night, and overall knee function
  • More effective if the affected knee is regularly used
  • Can be beneficial for patients in all stages of osteoarthritis
  • Minimal side effects

Side effects and recommendations

  • Ask somebody to drive you home, and rest for 24 hours
  • Ice the knee for 2-3 hours
  • Avoid excessive activity for 48 hours after the injection
  • Rarely are there systemic adverse reactions to Synvisc One possible side effects include
  • Local pain and swelling, will usually ease in a few days
  • Inform your doctor if you have an allergy to birds, feathers or eggs
  • Complications related to the procedure e.g. infection at wound site

Moderate Knee Synvisc-One Injection

Severe Knee Synvisc-One Injection

Synvisc-One Injection


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